The EPA has over 300 chemicals for use against these bugs. Consumers can use most of these. However, there are a few that a professional exterminator can use. The information comes from the EPA’s evaluation of their safety and effectiveness.

These 300 pest control products fall into seven chemical classes. Another class known as Dichlorvos (DDP) is also registered for particular use ? treating small enclosures. Each of these eight chemical classes kills bed bugs a different way. This is helpful because it lessens the likelihood that bed bugs will grow resistant to them.

Bed bugs

Pyrethrins and Pyrethroids

This is the most common form of pest control that an exterminator will use. It isn’t only used for bed bug control, but also for controlling other indoor pests as well. Sometimes these products are available as a total release fogger.

Pyrethrins are a form of botanical insecticide. They’re derived from chrysanthemum flowers. On the other hand, Pyrethroids are synthetic chemicals that work in the same way as pyrethrins. Both of these chemicals perform bed bug removal by flushing them out of where they’re hiding and killing them. Unfortunately, some bed bugs have grown resistant to these chemicals. When this happens, the chemicals will only temporarily flush the bugs out, causing them to move to a new place.

For those ?resistant bed bug strains, your exterminator will use a combination product.? says This typically has several pyrethroid and pyrethrin active ingredients in it. There are also some that combine various chemical classes within their single product. Both of these formulations allow for improved bed bug control. The same holds true for switching to an entirely different chemical class.

Bed bug control


When your exterminator uses a desiccant, they destroy the bed bug’s outer, waxy, protective coating. This leads to the bed bugs dying from dehydration, which is a valuable form of bed bug control because it’s a real mode. Bed bugs can’t grow resistant to this like they can grow resistant to other forms of pesticides that have varying modes of action. Additionally, this modality is long-lasting, and it doesn’t disturb the bed bug’s normal activities.

Two examples of ?this chemical class are Diatomaceous Earth and Boric acid.? according to When an exterminator uses either of these it’s important they make sure that they use a product registered by the EPA for bed bug control. Using a desiccant that’s not labeled for bed bugs poses a greater inhalation risk for people. This includes desiccants that the EPA labels food-grade or for swimming pool use. It’s also important to understand the limited usage of this chemical class. You can only use it in cracks and crevices. They do this in hopes of reducing the risk of inhalation.


There is only one biochemical pesticide that your exterminator can use for bed bug removal: cold pressed neem oil. This is pressed directly from a Neem tree’s seeds. The Neem tree is a tropical evergreen tree found growing throughout Africa and Southeast Asia. In the oil, there are various compounds known for their insecticidal and medicinal properties. For this reason, the oil is also used in making shampoo, soap, toothpaste, and cosmetics. When scientists performed trials on bed bug adults, nymphs, and eggs.


Currently, the only pyrrole pest control an exterminator can use for bed bug removal is Chlorfenapyr. This is a pro-insecticide compound meaning its biological activity depends on another chemical activating with it. When this happens, it forms a new chemical that disrupts functioning in the bed bug’s cells. This ultimately causes its death.


These are a synthetic form of nicotine. As such, this form of pest control works on the bed bug’s nicotine receptors, which are found in its nervous system. When this happens, the bed bug’s nerves fire continually until they eventually fail. This is a different mode of pest control so even if bed bugs grow resistant to other forms of pest control, this bed bug removal mode may still work on them.

Insect Growth Regulators

This form of pest control mimics a green insect’s growth hormones. When an exterminator uses them the insect growth regulator works in one of two ways.

The first is that it alters chitin’s production. This is the compound that insects use when making their exoskeleton (their hard, external ?shell?).

Secondly, insect growth regulators can also affect the insect’s development either by forcing rapid development or stopping its development altogether.